Innovations in Cellular Therapy for COPD

Chronic obstructive pulmonary disease or COPD ranks as the third leading cause of death in the United States trailing just behind heart disease and cancer. For most COPD patients vigilance symptom management means better quality of life. However, progression of the disease is inevitable. For patients like Larry disease progression is the only sure thing about COPD, take a look. Well, I first was diagnosed with COPD in 2004. I had already stopped running just about that time just simply because it’s so difficult for me to catch my breath and continue on. It seems like every year I noticed a little bit of a change even over the last year or two I noticed a change from one year to the next little less capacity to breathe. It affected my lifestyle, mostly because I was active with physical training and of classes for physical training for seniors and it was getting to the point where I couldn’t exert during those and even simple things like working around the yard I would get up I’d have to stop and catch my breath sometimes just go back down just to be able to breathe for a moment.

COPD is always progressive but then aging is as well and if you can stop the COPD rapid progression then I would progress normally in lung function and that’s really what I was looking, for a way for me not to have to rely on extraordinary means to catch my breath and to me feel better. Patients like Larry are not alone, in fact COPD affects over 24 million Americans. Despite advances in medicine the standard of care for COPD treatment has remained relatively unchanged over the past few decades leaving patients with few options. What if there was a way to potentially slow the progression of the disease using the patient’s own stem cells? Well joining me today to discuss the alternative to traditional treatment options for COPD is Dr. James St. Louis from the Lung Institute. Doctor, thank you so much for joining us today. Thank you for having me Ereka. So let’s get right to it doctor, what exactly is COPD and what are the current treatments? COPD is chronic obstructive pulmonary disease, which includes chronic bronchitis and emphysema and the traditional treatments right now would be nebulizers, medication, and a variety of other treatments that treat the symptoms of the disease.

To actually treat the disease would be a lung transplant. At the Lung Institute we treat the COPD in other lung diseases with stem cell therapy. Stem cells are the body’s natural healing cells they reduce the inflammation in your body. Inflammation causes many diseases in the body so you can use your own cells to decrease the inflammation. So the process of harvesting stem cell sounds incredibly complicated, what is that process like? It’s actually very simple, you can take your blood and separate the stem cells out and the other way of doing it is using your bone marrow which is also a very simple procedure and then we separate out the stem cells and then put them back into your body using an IV. So how are you getting the stem cells to target the lung specifically? Stem cells after we harvest them and return them into your body when they circulate to the right side of your heart and then from the right side of the heart they’re pushed into the lungs but the stem cells go into a part of the lung called a pulmonary trap and they stay in this pulmonary trap and then they are dispersed primarily to the lung.

So, then what are the risks and what are the results? The risks are very minimal if you just sit back and think about it because it’s your own cells. Right. You’re not introducing anything foreign into your body suit the risks are very minimal. The results show at about three months, the patients have an increased quality of life. Some people had fairly severe disease and they were on oxygen 24 hours a day so now they’re on oxygen much less, but they can go simple things, I go to the grocery store, do day-to-day activities versus how they were before. So, what is the ultimate goal at the Lung Institute? Our goal from the technical part is to increase in some cases your lung function which goes hand-in-hand with increasing your quality of life. This sounds like a great option for so many people and we met with Larry at the top of the show if you remember so let’s check in with him again to see how he’s doing.

In 2014 my condition was progressing of course to the point where I couldn’t participate in things as well as I wanted to and I did read an ad in the newspaper about Lung Institute. I made the decision to proceed and the procedure was very simple, straightforward, and not uncomfortable at all. They asked me to keep a journal and the results of that was that I saw that over a period of about three weeks I gradually had some improvement in lung function and ability to do my exercise programs. After my last treatment I had really good results and before that I couldn’t breathe very well and had to let up and rest during my aerobic exercises but right after the treatment I found that I was able to do the whole exercise and I didn’t have any problem with breathing.

With the positive results I’ve had, I really look forward to the future perhaps we can get more involved in stem cells, perhaps we can actually make better things happen and I’m really hopeful for the future particularly not from necessarily for myself but for others who may have problems similar to mine that there is may be a path to recovery. We are so happy to see that Larry is doing well now Doctor the Lung Institute uses stem cell therapy to treat other lung diseases as well? That’s correct. We treat major pulmonary lung diseases which as I said before COPD which is emphysema, chronic bronchitis, and then we also treat interstitial lung disease, which one of those is pulmonary fibrosis.

For those out there who are suffering from COPD or other lung disease they now know that there’s an alternative thank you doctor so much for joining us! For more on the alternative treatment options discussed here today go to lung institute dot com and of course you can find all of these resources on our website as well access health dot TV. Thank you so much doctor! (Music).

Recovery from COPD?

Hello, in this episode of health sketch where we will talk about chronic obstructive pulmonary disease The term COPD means chronic obstructive pulmonary disease It is a little complicated naming, but it becomes meaningful when interpreted word for word “Chronic” means a disease that cannot be cured ‘Blockage’ describes how illness makes breathing difficult And “pulmonary disease” means that it affects the lungs Obstructive pulmonary disease has become more common worldwide It is now the third largest cause of death. The true number of people suffering from the disease is much higher than the currently counted number Because many people do not know that they have this disease Early diagnosis is very important, as treatment helps to slow down damage to the lungs.

Most of the time, smoking is a cause of chronic obstructive pulmonary disease Particles from tobacco smoke inflame and irritate the lungs So stopping smoking is the best thing smokers can do However, COPD also affects non-smokers. Environmental pollution and rare genetic diseases can also lead to infection But what exactly is COPD? First let’s see how the lungs work. The lungs are a spongy network of people and alveoli. At inspiration, air passes through the airways that get smaller and smaller and end up in the tiny air sacs. In these alveoli, oxygen travels from the air to the blood and carbon dioxide is eliminated When developing chronic obstructive pulmonary disease, inflammation over time causes permanent damage to the people and air sacs in the lungs. The bronchi becomes inflamed, swollen and filled with mucus, which impedes airflow The alveoli lose their structure and spongy nature, so they cannot be easily filled and discharged, This makes the exchange of oxygen and carbon dioxide difficult.

These pulmonary changes cause the main symptoms of COPD: shortness of breath, wheezing, coughing and phlegm Symptoms worsen gradually over time, making daily activities more difficult. You should see a doctor if you have these symptoms. Early treatment of COPD can make a big difference. How is chronic obstructive pulmonary disease diagnosed and how is it treated? After checking your symptoms, your doctor can arrange breathing tests Find out how difficult and fast the air is getting out of your lungs. If you are confirmed to have COPD, the doctor recommends the most appropriate treatment To help you cope with the symptoms of the disease and control it. For smokers, stopping smoking is the most effective solution. The Inhaler (which comes in many forms) Contains medications that help expand the airways and reduce inflammation.

Using inhalers can be difficult, but knowing the correct method is necessary for the medication to be effective. Nurses, doctors, and pharmacists can help teach the correct way to use the inhaler People with this disease should be vaccinated to help prevent chest infections, Regular checks should be performed to monitor the overall course of treatment can be “stepped up” according to the patient’s specific needs Other medications may also be prescribed. Sometimes, patients experience severe shortness of breath called ‘exacerbation episodes’. Causes of these attacks include infection, cold weather or other irritants It is important to distinguish these ‘relapses’, The sooner the treatment is given, the lower the risk of worsening symptoms. Antibiotics and stimulants are often used, and sometimes oxygen therapy is needed. In complex cases, hospitalization may be required, but in mild cases, it is possible That the treatment be given effectively at home.

Besides medications, there are many other ways to improve symptoms of COPD. The ‘Pulmonary Rehabilitation Program’ is a great way to get an education and support This is according to your needs, as it has proven to be one of the best ways to improve the quality of life. The program may include: physical therapy for the chest to help overcome shortness of breath and control phlegm Light and regular exercise Dietary advice, as weight loss is common in patients with COPD Counseling to help lift your spirits when you feel low on frustration or anxiety Support groups, to connect with others with the same experiences, questions and feelings Remember, stopping smoking remains the most important catalyst. You can always quit smoking. This may be difficult, but local smoking cessation services are available, It is worth noting that the chances of quitting smoking increase when using their support. Alternatives to nicotine and other medications can reduce your craving for smoking and have been shown to be effective.

We have talked in this issue of health sketch about what is chronic obstructive pulmonary disease and its causes. We talked about the main symptoms and treatments; and the ways in which lifestyle changes can make a big difference. We hope that this health lesson on COPD has been beneficial to you and those around you. HealthSketch “Health for all”.